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Wobenzym Autoimmune, Toxic, Hepatitis B, Hepatitis C Studies

Autoimmune Hepatitis, Toxic Hepatitis, Hepatitis B, Hepatitis C

Wobenzym in complex therapy of chronic liver diseases
Vasilenko A. M., Svec S. V. Wobenzym in complex therapy of chronic liver diseases. State Medical Academy in Dnepropetrovsk. II National Congress of Rheumatologists in the Ukraine, Kiev, 1997

Current complex therapy of chronic liver diseases focuses on elimination of basic pathogenetic syndroms of the disease. Glucocorticoids (GC) are the most effective in the treatment of chronic autoimmune hepatitis (CAH) and active liver cirrhosis (LC) with a significant autoimmune process. They appear to be effective regulators of immune reaction which suppress antibody production. One of the undesirable side-effects of GC is formation of circulating middle size immune complexes (CIC) which intensify cytolytic syndrom ( 1, 2, 4). One of the main characteristics of CIC - pathogenesity - is mainly determined by the size of complexes. Pathogenesity is caused, among others factors, also by a quantitative relation between antigen and antibody. During overproduction of antibodies against any antigen or in the case of equivalent relation when antigen is fully or partially bound, large CIC are formed. Mild excess of antigen over appropriate antibody (ratio 3:2) leads to a formation of middle sized immune complexes. Insufficient antibody production causes a formation of low molecular weight complexes. Literature data (l, 2, 4) show that cytolysis is higher when middle size CIC prevail. Optimal conditions for middle size CIC formation arise in 2nd - 3rd week of the treatment by big doses of GC. Wide use of GC is limited also by risk of possible side-effects: pathological changes in organs of digestive system and kidney, insufficient anti-inflammatory effect, impossible induction of remission of the disease. All above mentioned facts speak for a necessity to search for new methods to treat chronic liver diseases. Systemic enzyme therapy seems to be one of the prospective options.

Antioxidant resveratrol significantly enhanced replication of hepatitis C virus

AIM: To elucidate the effect of antioxidants, resveratrol (RVT) and astaxanthin (AXN), on hepatitis C virus (HCV) replication.

Study Finds that Natural Bioflavonoids Kill Hepatitis C Virus

Hepatitis C is an infectious disease of the liver that can cause miserable symptoms including fatigue, lack of appetite, abdominal pain, nausea and vomiting. Caused by a virus, hepatitis C affects about 200 million people worldwide. In the U.S. alone, one to two percent of the population is infected. Not only can this infectious disease cause scarring of the liver, cirrhosis, and eventually liver failure, but a significant number of people with hepatitis C also develop sometimes fatal liver disease or cancer.

Association of caffeine intake and histological features of chronic hepatitis C


BACKGROUND & AIMS: The severity of chronic hepatitis C (CHC) is modulated by host and environmental factors. Several reports suggest that caffeine intake exerts hepatoprotective effects in patients with chronic liver disease. The aim of this study was to evaluate the impact of caffeine consumption on activity grade and fibrosis stage in patients with CHC.

NEW Studies Reveal Alarming Hidden Cause of Breast Cancer

By Russell L. Blaylock, MD, CCN

Vaccines Increase Cancer RiskBreast cancer is one of the leading causes of cancer death in women worldwide and breast cancer rates are increasing rapidly.

A compelling number of studies, though not all, have shown that free iron concentrations in breast tissue, especially the ductal tissue, is playing a major role in stimulating cancer development and eventual progression to aggressive, deadly cancers.1,2

Cancers are Very Dependent on Iron

Iron is needed for DNA replication in rapidly dividing cells.3

A recent report from the Department of Biomolecular Sciences in Urbino Italy, found that fluid taken from the nipple of cancer patients contained significantly higher levels of aluminum than did nipple fluid taken from women without breast cancer—approximately twice as much aluminum.4

A number of studies have found that extracting nipple fluid by a breast pump (in both premenopausal and postmenopausal women) is a simple way to study the microenvironment of the ductal tissue, the site of development of most breast cancers.5

Examining this ductal fluid is an excellent way to measure such things as iron levels, ferritin (an iron-binding protein), CRP (a measure of breast inflammation) and aluminum.

The researchers also found that women with breast cancer had much higher levels of ferritin, an iron transport protein, in their breast fluid, which was 5X higher in women with breast cancer.6

This observation has been confirmed in other studies.

In previous studies researchers found that one's intake of iron did not necessarily correlate with risk of breast cancer, but rather the release of iron from its protective proteins, such as ferritin and transferrin was critical.7

This distinction is very important and explains why some studies found no link between iron intake in the diet and breast cancer incidence.8

cannabis use on severity of hepatitis C disease (2008)


BACKGROUND & AIMS: Complications of HCV infection are primarily related to the development of advanced fibrosis and whether cannabis use is a risk factor for more severe fibrosis is controversial.

METHODS: Baseline data from a prospective cohort study of 204 persons with chronic HCV infection were used for analysis. The outcome was fibrosis score on biopsy, and the primary predictor evaluated was daily cannabis use.

phase II clinical trial SOC and Boceprevir - Join the Suit

Lloyd Wright,
An email friend referred your site. I am currently in a federal law suit for permanent injury sustained from my participation in a clinical trial of PegIntron / Rebetol / Boceprevir. I suffer multi-system sarcoidosis with occular, renal and pulmonary involvement caused by PegIntron and Rebetol treatment.

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