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Library of Scientific Studies Funded and Published by others and Hepatitis C articles from other sources..

Shark Molecule Kills Human Viruses, Too

A molecule found in sharks appears to be able to wipe out human liver viruses, such as hepatitis, new research has found. 

"Sharks are remarkably resistant to viruses," study researcher Michael
Zasloff, of the Georgetown University Medical Center, told LiveScience.
Zasloff discovered the molecule, squalamine, in 1993 in the dogfish
shark, a small- to medium-size shark found in the Atlantic, Pacific, and
Indian Oceans.

"It looked like no other compound that had been described in any animal
or plant before. It was something completely unique," Zasloff said. The
compound is a potent antibacterial and has shown efficacy in treating
human cancers and an eye condition known as macular degeneration, which
causes blindness.

Silibinin monotherapy prevents graft infection after orthotopic liver transplantation in a patient with chronic hepatitis C

  from Jules: many studies in the past few years conducted by Peter Ferenci have shown IV silibin to have significant antiviral efficacy against HCV (see link below).

Naringenin inhibits production of hepatitis C virus

Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism.
Goldwasser J
, Cohen PY, Lin W, Kitsberg D, Balaguer P, Polyak SJ, Chung RT, Yarmush ML, Nahmias Y.

Source

Center for Engineering in Medicine, Shriners Burns Hospital, Boston, MA, USA; Harvard-MIT Division of Health Science and Technology, Cambridge, MA, USA; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Abstract
BACKGROUND & AIMS:

Hepatitis C virus (HCV) infection affects 3% of the world population and is the leading cause of chronic liver disease worldwide. Current standard of care is effective in only 50% of the patients, poorly tolerated, and associated with significant side effects and viral resistance. Recently, our group and others demonstrated that the HCV lifecycle is critically dependent on host lipid metabolism and that its production is metabolically modulated.

METHODS:

The JFH1/Huh7.5.1 full lifecycle model of HCV was used to study the antiviral effects of naringenin on viral replication, assembly, and production. Activation of PPAR? was elucidated using GAL4-PPAR? fusion reporters, PPRE reporters, qRT-PCR, and metabolic studies. Metabolic results were confirmed in primary human hepatocytes

Rawesome Foods Target of Multi Agency Raid

WHO: Hospital Stay Riskier Than Flying

Millions of people die each year from medical errors and infections linked to healthcare and going into hospital is far riskier than flying, the World Health Organization said on Thursday.

"If you were admitted to hospital tomorrow in any country ... your chances of being subjected to an error in your care would be something like one in 10. Your chances of dying due to an error in healthcare would be 1 in 300," Liam Donaldson, the WHO's newly appointed envoy for patient safety, told a news briefing.

FDA's scheme to outlaw all nutritional supplements created after 1994 would destroy millions of jobs and devastate economy

Yesterday we reported on the FDA's new scheme for outlawing nearly all nutritional supplements formulated after October, 1994 (http://www.naturalnews.com/032912_F...). That was just the beginning of this story, because a detailed analysis of the proposed new regulation reveals extremely disturbing revelations that would absolutely gut the nutritional products industry if these regulations are put into practice.

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